LncRNA GAS5 Competitively Combined With miR-21 Regulates PTEN and Influences EMT of Peritoneal Mesothelial Cells via Wnt/β-Catenin Signaling Pathway

LncRNA GAS5 Competitively Combined With miR-21 Regulates PTEN and Influences EMT of Peritoneal Mesothelial Cells via Wnt/β-Catenin Signaling Pathway

ObjectiveEpithelial-mesenchymal transition (EMT) is an important factor leading to peritoneal fibrosis (PF) in end-stage renal disease (ESRD) patients. The current research aimed to evaluate the effect of long non-coding RNA growth arrest-specific 5 (lncRNA GAS5) in human peritoneal mesothelial cell...

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Bibliographic Details
Main Authors: Yi Fan, Xingxu Zhao, Jianfei Ma, Lina Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Physiology
Subjects:
lncRNA GAS5
miR-21
PTEN
Wnt/β-catenin
EMT
HPMCs
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.654951/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.654951/full

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