Neutrophil Elastase Deficiency Ameliorates Myocardial Injury Post Myocardial Infarction in Mice

Neutrophil Elastase Deficiency Ameliorates Myocardial Injury Post Myocardial Infarction in Mice

Neutrophils are recruited into the heart at an early stage following a myocardial infarction (MI). These secrete several proteases, one of them being neutrophil elastase (NE), which promotes inflammatory responses in several disease models. It has been shown that there is an increase in NE activity...

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Bibliographic Details
Main Authors: Yukino Ogura, Kazuko Tajiri, Nobuyuki Murakoshi, DongZhu Xu, Saori Yonebayashi, Siqi Li, Yuta Okabe, Duo Feng, Yuzuno Shimoda, Zoughu Song, Haruka Mori, Zixun Yuan, Kazutaka Aonuma, Masaki Ieda
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
neutrophil elastase
myocardial infarction
apoptosis
remodeling
neutrophil
sivelestat
Online Access:https://www.mdpi.com/1422-0067/22/2/722

Internet

https://www.mdpi.com/1422-0067/22/2/722

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