In vivo imaging of early stages of rheumatoid arthritis by α5β1-integrin-targeted positron emission tomography

In vivo imaging of early stages of rheumatoid arthritis by α5β1-integrin-targeted positron emission tomography

Abstract Background Rheumatoid arthritis (RA) is one of the most common rheumatic diseases. Joint inflammation and pathological growth of joint cartilage cause swollen and painful joints, which severely diminishes the patients’ life quality. There is no causal treatment. Symptomatic therapies should...

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Bibliographic Details
Main Authors: Johannes Notni, Florian T. Gassert, Katja Steiger, Peter Sommer, Wilko Weichert, Ernst J. Rummeny, Markus Schwaiger, Horst Kessler, Reinhard Meier, Melanie A. Kimm
Format: Article
Language:English
Published: SpringerOpen 2019-09-01
Series:EJNMMI Research
Subjects:
Rheumatoid arthritis
Positron emission tomography
Integrins
Animal models
Collagen-induced arthritis
Immunohistochemistry
Online Access:http://link.springer.com/article/10.1186/s13550-019-0541-6

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http://link.springer.com/article/10.1186/s13550-019-0541-6

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