Third generation cephalosporins and piperacillin/tazobactam have distinct impacts on the microbiota of critically ill patients

Abstract Effective implementation of antibiotic stewardship, especially in critical care, is limited by a lack of direct comparative investigations on how different antibiotics impact the microbiota and antibiotic resistance rates. We investigated the impact of two commonly used antibiotics, third-g...

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Bibliographic Details
Main Authors: Hasinika K. A. H. Gamage, Carola Venturini, Sasha G. Tetu, Masrura Kabir, Vineet Nayyar, Andrew N. Ginn, Belinda Roychoudhry, Lee Thomas, Mitchell Brown, Andrew Holmes, Sally R. Partridge, Ian Seppelt, Ian T. Paulsen, Jonathan R. Iredell
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85946-4