Nanoliposome-Encapsulated Brinzolamide-hydropropyl-β-cyclodextrin Inclusion Complex: A Potential Therapeutic Ocular Drug-Delivery System

Nanoliposome-Encapsulated Brinzolamide-hydropropyl-β-cyclodextrin Inclusion Complex: A Potential Therapeutic Ocular Drug-Delivery System

Novel ocular drug delivery systems (NODDSs) remain to be explored to overcome the anatomical and physiological barriers of the eyes. This study was to encapsulate brinzolamide (BRZ)-hydropropyl-β-cyclodextrin (HP-β-CD) inclusion complex (HP-β-CD/BRZ) into nanoliposomes and investigate its potential...

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Bibliographic Details
Main Authors: Fazhan Wang, Xingting Bao, Aiping Fang, Huili Li, Yang Zhou, Yongmei Liu, Chunling Jiang, Jinhui Wu, Xiangrong Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Pharmacology
Subjects:
brinzolamide
cyclodextrin
inclusion complex
nanoliposomes
intraocular pressure
ocular drug delivery
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00091/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00091/full

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