A doublecortin-domain protein of Toxoplasma and its orthologues bind to and modify the structure and organization of tubulin polymers

A doublecortin-domain protein of Toxoplasma and its orthologues bind to and modify the structure and organization of tubulin polymers

Abstract Background TgDCX is a doublecortin-domain protein associated with the conoid fibers, a set of strongly curved non-tubular tubulin-polymers in Toxoplasma. TgDCX deletion impairs conoid structure and parasite invasion. TgDCX contains two tubulin-binding domains: a partial P25α and the DCX/dou...

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Bibliographic Details
Main Authors: Jacqueline M. Leung, Eiji Nagayasu, Yu-Chen Hwang, Jun Liu, Phillip G. Pierce, Isabelle Q. Phan, Robin A. Prentice, John M. Murray, Ke Hu
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Molecular and Cell Biology
Online Access:http://link.springer.com/article/10.1186/s12860-020-0249-5

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http://link.springer.com/article/10.1186/s12860-020-0249-5

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