The cis-trans binding strength defined by motif frequencies facilitates statistical inference of transcriptional regulation

The cis-trans binding strength defined by motif frequencies facilitates statistical inference of transcriptional regulation

Abstract Background A key problem in systems biology is the determination of the regulatory mechanism corresponding to a phenotype. An empirical approach in this regard is to compare the expression profiles of cells under two conditions or tissues from two phenotypes and to unravel the underlying tr...

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Bibliographic Details
Main Authors: Yance Feng, Sheng Zhang, Liang Li, Lei M. Li
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Bioinformatics
Subjects:
BASE
Statistical inference
Transcriptional regulation
PUFA
DHA
EPA
Online Access:http://link.springer.com/article/10.1186/s12859-019-2732-6

Internet

http://link.springer.com/article/10.1186/s12859-019-2732-6

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