Superiority of allorestricted T cells in Immunotherapy of Cancer:From Sharks to Men
Men and sharks are both jawed vertebrates at the top of the food chain. Sharks are the first extant to develop adaptive immunity preserved to man throughout jawed vertebrates. We hy-pothesize here, that T cell receptor / major histocompatibility complex (TCR/MHC) interac-tions developed as the defen...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2013-05-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00100/full |