Accuracy of immunodiagnostic tests for active tuberculosis using single and combined results: a multicenter TBNET-Study.

BACKGROUND: The clinical application of IFN-gamma release assays (IGRAs) has recently improved the diagnosis of latent tuberculosis infection. In a multicenter study of the Tuberculosis Network European Trialsgroup (TBNET) we aimed to ascertain in routine clinical practice the accuracy of a novel as...

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Main Authors: Delia Goletti, Stefania Carrara, Ornella Butera, Massimo Amicosante, Martin Ernst, Ilaria Sauzullo, Vincenzo Vullo, Daniela Cirillo, Emanuele Borroni, Roumiana Markova, Roumiana Drenska, José Dominguez, Irene Latorre, Claudio Angeletti, Assunta Navarra, Nicola Petrosillo, Francesco Nicola Lauria, Giuseppe Ippolito, Giovanni Battista Migliori, Christoph Lange, Enrico Girardi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2561073?pdf=render