Synthetic High-Density Lipoprotein-Mediated Targeted Delivery of Liver X Receptors Agonist Promotes Atherosclerosis Regression

Synthetic High-Density Lipoprotein-Mediated Targeted Delivery of Liver X Receptors Agonist Promotes Atherosclerosis Regression

Targeting at enhancing reverse cholesterol transport (RCT) is apromising strategy for treating atherosclerosis via infusion of reconstitute high density lipoprotein (HDL) as cholesterol acceptors or increase of cholesterol efflux by activation of macrophage liver X receptors (LXRs). However, systemi...

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Bibliographic Details
Main Authors: Yanhong Guo, Wenmin Yuan, Bilian Yu, Rui Kuai, Wenting Hu, Emily E. Morin, Minerva T. Garcia-Barrio, Jifeng Zhang, James J. Moon, Anna Schwendeman, Y. Eugene Chen
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:EBioMedicine
Subjects:
Atherosclerosis
Liver X receptors
High-density lipoprotein
Reverse cholesterol transport
Macrophage
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396417305029

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http://www.sciencedirect.com/science/article/pii/S2352396417305029

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