The Paired Siglecs in Brain Tumours Therapy: The Immunomodulatory Effect of Dexamethasone and Temozolomide in Human Glioma In Vitro Model

The Paired Siglecs in Brain Tumours Therapy: The Immunomodulatory Effect of Dexamethasone and Temozolomide in Human Glioma In Vitro Model

The paired sialic acid-binding immunoglobulin like lectins (Siglecs) are characterized by similar cellular distribution and ligand recognition but opposing signalling functions attributed to different intracellular sequences. Since sialic acid—Siglec axis are known to control immune homeostasis, the...

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Bibliographic Details
Main Authors: Przemyslaw Wielgat, Natalia Wawrusiewicz-Kurylonek, Robert Czarnomysy, Karol Rogowski, Krzysztof Bielawski, Halina Car
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
Siglec
glioma
microglia
dexamethasone
temozolomide
Online Access:https://www.mdpi.com/1422-0067/22/4/1791

Internet

https://www.mdpi.com/1422-0067/22/4/1791

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