Inhibition of TREM-1 and Dectin-1 Alleviates the Severity of Fungal Keratitis by Modulating Innate Immune Responses.

To explore the possibility that inhibiting triggering receptor expressed on myeloid cells-1 (TREM-1) and Dendritic cell-associated C-type lectin-1(Dectin-1) could modulate the innate immune response and alleviate the severity of corneal fungal keratitis.TREM-1 and Dectin-1 expression was detected in...

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Bibliographic Details
Main Authors: Jing Zhong, Weilan Huang, Qiuchan Deng, Minhao Wu, Huaili Jiang, Xiaolei Lin, Yifang Sun, Xi Huang, Jin Yuan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4786258?pdf=render