Tc17/IL-17A Up-Regulated the Expression of MMP-9 via NF-κB Pathway in Nasal Epithelial Cells of Patients With Chronic Rhinosinusitis

Tc17/IL-17A Up-Regulated the Expression of MMP-9 via NF-κB Pathway in Nasal Epithelial Cells of Patients With Chronic Rhinosinusitis

Chronic rhinosinusitis (CRS) is a common chronic inflammatory disease of the upper airways involving nasal cavity and sinus. Deriving both from its clinical complexity with protean clinical manifestations as well its pathogenetic heterogeneity, the molecular mechanisms contributing to the pathogenes...

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Bibliographic Details
Main Authors: Xiaohong Chen, Lihong Chang, Xia Li, Jiancong Huang, Luoying Yang, Xiaoping Lai, Zizhen Huang, Zhiyuan Wang, Xifu Wu, Jun Zhao, Joseph A. Bellanti, Song Guo Zheng, Gehua Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
chronic rhinosinusitis
IL-17A
Tc cells
nasal epithelial cells
MMP-9
NF-κB
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02121/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02121/full

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