Where Do Bone-Targeted Agents RANK in Breast Cancer Treatment?
Breast cancer cells preferentially metastasise to the skeleton, owing, in part, to the fertile environment provided by bone. Increased bone turnover releases growth factors that promote tumour cell growth. In turn, tumour cells release factors that stimulate further bone turnover, resulting in a vic...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-08-01
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Series: | Journal of Clinical Medicine |
Subjects: | |
Online Access: | http://www.mdpi.com/2077-0383/2/3/89 |