Where Do Bone-Targeted Agents RANK in Breast Cancer Treatment?

Breast cancer cells preferentially metastasise to the skeleton, owing, in part, to the fertile environment provided by bone. Increased bone turnover releases growth factors that promote tumour cell growth. In turn, tumour cells release factors that stimulate further bone turnover, resulting in a vic...

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Bibliographic Details
Main Authors: Roger von Moos, Ian Haynes
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:http://www.mdpi.com/2077-0383/2/3/89