Autophagy Inhibitor (LY294002) and 5-fluorouracil (5-FU) Combination-Based Nanoliposome for Enhanced Efficacy Against Esophageal Squamous Cell Carcinoma

Autophagy Inhibitor (LY294002) and 5-fluorouracil (5-FU) Combination-Based Nanoliposome for Enhanced Efficacy Against Esophageal Squamous Cell Carcinoma

Abstract In this study, 5-fluorouracil (5-FU) and LY294002 (LY)-loaded PEGylated nanoliposome was prepared to target esophageal squamous cell carcinoma (ESCC). The particles were characterized in terms of physicochemical and biological parameters. The co-delivery of autophagy inhibitor and chemother...

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Bibliographic Details
Main Authors: Ye Feng, Yongjian Gao, Dayu Wang, Zhonghang Xu, Weixuan Sun, Ping Ren
Format: Article
Language:English
Published: SpringerOpen 2018-10-01
Series:Nanoscale Research Letters
Subjects:
Esophageal cancer
5-fluorouracil
Autophagy inhibitor
Apoptosis
Liposome
Online Access:http://link.springer.com/article/10.1186/s11671-018-2716-x

Internet

http://link.springer.com/article/10.1186/s11671-018-2716-x

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