NMDA Receptor Hypofunction in the Aging-Associated Malfunction of Peripheral Tissue

NMDA Receptor Hypofunction in the Aging-Associated Malfunction of Peripheral Tissue

Glutamatergic transmission through NMDA receptors (NMDARs) is important for the function of peripheral tissues. In the bone, NMDARs and its co-agonist, D-serine participate in all the phases of the remodeling. In the vasculature, NMDARs exerts a tonic vasodilation decreasing blood perfusion in the c...

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Bibliographic Details
Main Authors: Angélica Rivera-Villaseñor, Frida Higinio-Rodríguez, Laura Nava-Gómez, Bárbara Vázquez-Prieto, Isnarhazni Calero-Vargas, Rafael Olivares-Moreno, Mónica López-Hidalgo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Physiology
Subjects:
hypofunction of NMDA receptor
aging
skin turnover
bone remodelling
glomerulus
D-serine
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.687121/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.687121/full

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