DNA methylation analysis of the tumor suppressor gene CDKN2B in Brazilian leukemia patients

The aim of this work was to evaluate the methylation profile of the p15 (CDKN2B) gene in Brazilian patients with leukemia and to correlate the CDKN2B gene expression with the percentage of methylated CpG dinucleotides in its promoter region. Thirty-one samples from six patients with acute lymphocyti...

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Bibliographic Details
Main Authors: Patrícia Santos Pereira Lima, Greice Andreoti Molffeta, Amélia Góes de Araujo, Marco Antônio Zago, Wilson Araújo da Silva Jr.
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2008-01-01
Series:Genetics and Molecular Biology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000400005