Optimization of Ultrasound-Assisted Extraction Conditions Followed by Solid Phase Extraction Fractionation from <i>Orthosiphon stamineus Benth (Lamiace)</i> Leaves for Antiproliferative Effect on Prostate Cancer Cells

Optimization of Ultrasound-Assisted Extraction Conditions Followed by Solid Phase Extraction Fractionation from <i>Orthosiphon stamineus Benth (Lamiace)</i> Leaves for Antiproliferative Effect on Prostate Cancer Cells

Primarily, optimization of ultrasonic-assisted extraction (UAE) conditions of <i>Orthospihon stamineus</i> was evaluated and verified using a central composite design (CCD) based on three factors including extraction time (minutes), ultrasound amplitude (A), and solvent concentration (%)...

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Bibliographic Details
Main Authors: Siti Hasyimah Suhaimi, Rosnani Hasham, Mohamad Khairul Hafiz Idris, Hassan Fahmi Ismail, Nor Hazwani Mohd Ariffin, Fadzilah Adibah Abdul Majid
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Molecules
Subjects:
ultrasound-assisted extraction
central composite design
solid-phase extraction
rosmarinic acid
<i>orthospihon stamineus</i>
prostate cancer
antioxidant activity
Online Access:https://www.mdpi.com/1420-3049/24/22/4183

Internet

https://www.mdpi.com/1420-3049/24/22/4183

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