Progesterone at high doses reduces the growth of U87 and A172 glioblastoma cells: Proteomic changes regarding metabolism and immunity

Progesterone at high doses reduces the growth of U87 and A172 glioblastoma cells: Proteomic changes regarding metabolism and immunity

Abstract While pregnancy may accelerate glioblastoma multiforme (GBM) growth, parity and progesterone (P4) containing treatments (ie, hormone replacement therapy) reduce the risk of GBM development. In parallel, low and high doses of P4 exert stimulating and inhibitory actions on GBM growth, respect...

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Bibliographic Details
Main Authors: Meric A. Altinoz, Yasemin Ucal, Muazzez C. Yilmaz, İrem Kiris, Ozan Ozisik, Ugur Sezerman, Aysel Ozpinar, İlhan Elmaci
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Cancer Medicine
Subjects:
cell line
glioblastoma
neuroendocrine treatment
progesterone
proteomic
Online Access:https://doi.org/10.1002/cam4.3223

Internet

https://doi.org/10.1002/cam4.3223

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