Single nucleotide polymorphisms Rs1045642 C>T genetic alteration in ATP Binding Cassette Subfamily B Member 1 role in increasing everolimus toxicity in metastatic breast cancer

Breast cancer is one of the most devastating diseases in the world, the most diffused cancer in women. Despite the incredible progress made in the field, the mortality rate in the metastatic setting is still quite high. Among the different drugs used to treat this disease, the mTOR inhibitor everoli...

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Bibliographic Details
Main Authors: Simone Leggeri, Navid Sobhani
Format: Article
Language:English
Published: AIMS Press 2020-05-01
Series:AIMS Molecular Science
Subjects:
Online Access:https://www.aimspress.com/article/10.3934/molsci.2020001/fulltext.html