The Efficacy and Safety of the mTOR Signaling Pathway Activator, MHY1485, for in vitro Activation of Human Ovarian Tissue

The Efficacy and Safety of the mTOR Signaling Pathway Activator, MHY1485, for in vitro Activation of Human Ovarian Tissue

BackgroundPremature ovarian insufficiency (POI) is characterized by abnormal ovarian function before the age of 40. POI showed that primordial follicles developed in disorder. mTOR signaling plays a vital role in the process of follicle development. It has been verified that the mTOR signaling pathw...

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Bibliographic Details
Main Authors: Shuang Wu, Yining Wang, Haixiang Ding, Ningxia Sun, Yan Liu, Liang Wang, Fei Sheng, Honghong Zhang, Fu Yang, Wen Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Genetics
Subjects:
premature ovarian insufficiency
mTOR signaling pathway
MYH1485
in vitro activation
safety
DNA methylation
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.603683/full

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https://www.frontiersin.org/articles/10.3389/fgene.2020.603683/full

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