Synthesis, in vitro bioassays, and computational study of heteroaryl nitazoxanide analogs

Synthesis, in vitro bioassays, and computational study of heteroaryl nitazoxanide analogs

Abstract Antiprotozoal drug nitazoxanide (NTZ) has shown diverse pharmacological properties and has appeared in several clinical trials. Herein we present the synthesis, characterization, in vitro biological investigation, and in silico study of four hetero aryl amide analogs of NTZ. Among the synth...

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Bibliographic Details
Main Authors: Tasmia Ahmed, S. M. Abdur Rahman, Muhammad Asaduzzaman, Abul Bashar Mir Md. Khademul Islam, A. K. Azad Chowdhury
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Pharmacology Research & Perspectives
Subjects:
cytotoxicity assay
DHFR
E. coli
MAPK9
nitazoxanide
TS
Online Access:https://doi.org/10.1002/prp2.800

Internet

https://doi.org/10.1002/prp2.800

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