Systemic delivery of targeted nanotherapeutic reverses angiotensin II-induced abdominal aortic aneurysms in mice

Abstract Abdominal aortic aneurysm (AAA) disease causes dilation of the aorta, leading to aortic rupture and death if not treated early. It is the 14th leading cause of death in the U.S. and 10th leading cause of death in men over age 55, affecting thousands of patients. Despite the prevalence of AA...

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Bibliographic Details
Main Authors: Xiaoying Wang, Vaideesh Parasaram, Saphala Dhital, Nasim Nosoudi, Shahd Hasanain, Brooks A. Lane, Susan M. Lessner, John F. Eberth, Naren R. Vyavahare
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88017-w