A combination of transcription factors mediates inducible interchromosomal contacts

The genome forms specific three-dimensional contacts in response to cellular or environmental conditions. However, it remains largely unknown which proteins specify and mediate such contacts. Here we describe an assay, MAP-C (Mutation Analysis in Pools by Chromosome conformation capture), that simul...

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Bibliographic Details
Main Authors: Seungsoo Kim, Maitreya J Dunham, Jay Shendure
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-05-01
Series:eLife
Subjects:
3C
Online Access:https://elifesciences.org/articles/42499