A Composite Nanosystem as a Potential Tool for the Local Treatment of Glioblastoma: Chitosan-Coated Solid Lipid Nanoparticles Embedded in Electrospun Nanofibers

A Composite Nanosystem as a Potential Tool for the Local Treatment of Glioblastoma: Chitosan-Coated Solid Lipid Nanoparticles Embedded in Electrospun Nanofibers

Glioblastoma multiforme (GBM) is one of the most prevalent and aggressive brain tumors for which there is currently no cure. A novel composite nanosystem (CN), consisting of chitosan-coated Solid Lipid Nanoparticles (c-SLN) embedded in O-carboxymethyl chitosan (O-CMCS)-containing nanofibers (NFs), w...

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Bibliographic Details
Main Authors: Barbara Vigani, Caterina Valentino, Giuseppina Sandri, Roberta Listro, Francesca Fagiani, Simona Collina, Cristina Lanni, Maria Cristina Bonferoni, Carla M. Caramella, Silvia Rossi, Franca Ferrari
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Polymers
Subjects:
glioblastoma multiforme
solid lipid nanoparticles
coacervation
chitosan-coating
O-carboxymethyl chitosan
electrospinning
Online Access:https://www.mdpi.com/2073-4360/13/9/1371

Internet

https://www.mdpi.com/2073-4360/13/9/1371

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