Magnetic ion channel activation of TREK1 in human mesenchymal stem cells using nanoparticles promotes osteogenesis in surrounding cells

Magnetic ion channel activation technology uses superparamagnetic nanoparticles conjugated with targeting antibodies to apply mechanical force directly to stretch-activated ion channels on the cell surface, stimulating mechanotransduction and downstream processes. This technique has been reported to...

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Bibliographic Details
Main Authors: James R Henstock, Michael Rotherham, Alicia J El Haj
Format: Article
Language:English
Published: SAGE Publishing 2018-10-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/2041731418808695