Involvement of Capsaicin-Sensitive Lung Vagal Neurons and TRPA1 Receptors in Airway Hypersensitivity Induced by 1,3-β-D-Glucan in Anesthetized Rats

Involvement of Capsaicin-Sensitive Lung Vagal Neurons and TRPA1 Receptors in Airway Hypersensitivity Induced by 1,3-β-D-Glucan in Anesthetized Rats

Airway exposure to 1,3-β-D-glucan (β-glucan), an essential component of the cell wall of several pathogenic fungi, causes various adverse responses, such as pulmonary inflammation and airway hypersensitivity. The former response has been intensively investigated; however, the mechanism underlying β-...

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Bibliographic Details
Main Authors: You Shuei Lin, I-Hsuan Huang, Sheng-Hsuan Lan, Chia-Ling Chen, Yueh-Yin Chen, Nai-Ju Chan, Chun-Chun Hsu
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
airway hypersensitivity
capsaicin-sensitive lung vagal afferents
afferent sensitization
fungi
glucan
sensory neuron
Online Access:https://www.mdpi.com/1422-0067/21/18/6845

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https://www.mdpi.com/1422-0067/21/18/6845

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