Cerebrovascular Reactivity: Purpose, Optimizing Methods, and Limitations to Interpretation – A Personal 20-Year Odyssey of (Re)searching

The brain is a neurovascular organ. A stimulus-response approach is effective in interrogating the physiology of its vasculature. Ideally, the stimulus is standardized across patients, and in a single patient over time. We developed a standard stimulus and attempted to measure, classify, and interpr...

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Bibliographic Details
Main Authors: Joseph A. Fisher, David J. Mikulis
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.629651/full