Experimental Simulation of the Effects of an Initial Antibiotic Treatment on a Subsequent Treatment after Initial Therapy Failure

Therapy failure of empirical antibiotic treatments prescribed by primary care physicians occurs commonly. The effect of such a treatment on the susceptibility to second line antimicrobial drugs is unknown. Resistance to amoxicillin was rapidly induced or selected in E. coli at concentrations expecte...

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Bibliographic Details
Main Authors: Yanfang Feng, Nadine Händel, Marnix H. P. de Groot, Stanley Brul, Constance Schultsz, Benno H. ter Kuile
Format: Article
Language:English
Published: MDPI AG 2014-02-01
Series:Antibiotics
Subjects:
Online Access:http://www.mdpi.com/2079-6382/3/1/49