Duck TRIM32 Functions in IFN-β Signaling Against the Infection of H5N6 Highly Pathogenic Avian Influenza Virus

Duck TRIM32 Functions in IFN-β Signaling Against the Infection of H5N6 Highly Pathogenic Avian Influenza Virus

In mammals, tripartite motif 32 (TRIM32) is essential for regulating host innate immune responses to viral infections. However, the antiviral effect of TRIM32 in birds has not been reported. Here, we cloned the full-length duck TRIM32 (duTRIM32) cDNA from total spleen RNA of Peking duck. DuTRIM32 co...

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Bibliographic Details
Main Authors: Siyu Wu, Junsheng Zhang, Qian Xue, Jing Liu, Bingzhong Huang, Zhuoliang He, Jianni Huang, Shaopo Zu, Zuxian Chen, Bingbing Zhao, Ming Liao, Peirong Jiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
duck
TRIM32
STING
IFN-β
avian influenza virus
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00377/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00377/full

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