The transcriptome landscape of the carcinogenic treatment response in the blind mole rat: insights into cancer resistance mechanisms

The transcriptome landscape of the carcinogenic treatment response in the blind mole rat: insights into cancer resistance mechanisms

Abstract Background Spalax, the blind mole rat, developed an extraordinary cancer resistance during 40 million years of evolution in a subterranean, hypoxic, thus DNA damaging, habitat. In 50 years of Spalax research, no spontaneous cancer development has been observed. The mechanisms underlying thi...

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Bibliographic Details
Main Authors: Robert Altwasser, Arnon Paz, Abraham Korol, Irena Manov, Aaron Avivi, Imad Shams
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Genomics
Subjects:
Cancer
Fanconi anemia
Spalax
Cancer-resistance
Extracellular matrix
Online Access:http://link.springer.com/article/10.1186/s12864-018-5417-z

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http://link.springer.com/article/10.1186/s12864-018-5417-z

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