High IL-1α production was induced in the WBN/Kob-Leprfa type 2 diabetes mellitus rat model and inhibited by Syphacia muris infection

The novel WBN/Kob-Leprfa (fa/fa) congenic rat strain is considered a useful rat model of type 2 diabetes mellitus (T2DM). Accumulating findings suggest that low-grade inflammation is a causative factor in T2DM and that circulating levels of inflammatory cytokines are associated with insulin resistan...

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Bibliographic Details
Main Authors: Okamoto M., Ito R., Taira K., Ikeda T.
Format: Article
Language:English
Published: Sciendo 2018-03-01
Series:Helminthologia
Subjects:
Online Access:https://doi.org/10.1515/helm-2017-0050