Early-Onset Parkinson's Disease Caused by PLA2G6 Compound Heterozygous Mutation, a Case Report and Literature Review

Early-Onset Parkinson's Disease Caused by PLA2G6 Compound Heterozygous Mutation, a Case Report and Literature Review

PLA2G6 has been certified as a causative gene in patients with autosomal recessive early-onset Parkinson's disease (EOPD). We reported an EOPD case caused by PLA2G6 gene mutation, and performed neurological examination, genetic analysis, and multimodal neuroimaging to describe this phenotype. A...

Full description

Bibliographic Details
Main Authors: Ting Shen, Jing Hu, Yasi Jiang, Shuai Zhao, Caixiu Lin, Xinzhen Yin, Yaping Yan, Jiali Pu, Hsin-Yi Lai, Baorong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Neurology
Subjects:
Parkinson's disease
early-onset
PLA2G6
genetic analysis
neuroimaging
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00915/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.00915/full

Similar Items