Transcriptional Analysis of Human Skin Lesions Identifies Tryptophan-2,3-Deoxygenase as a Restriction Factor for Cutaneous Leishmania

Transcriptional Analysis of Human Skin Lesions Identifies Tryptophan-2,3-Deoxygenase as a Restriction Factor for Cutaneous Leishmania

Disease manifestation after infection with cutaneous Leishmania species is the result of a complex interplay of diverse factors, including the immune status of the host, the infecting parasite species, or the parasite load at the lesion site. Understanding how these factors impact on the pathology o...

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Bibliographic Details
Main Authors: Vasco Rodrigues, Sónia André, Hasnaa Maksouri, Tarik Mouttaki, Soumiya Chiheb, Myriam Riyad, Khadija Akarid, Jérôme Estaquier
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
cutaneous leishmanaisis
tryptophan-2
3-dioxygenase
Leishmania tropica
Leishmania major
parasite load
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00338/full

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https://www.frontiersin.org/article/10.3389/fcimb.2019.00338/full

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