DNA Methylation Patterns in the Early Human Embryo and the Epigenetic/Imprinting Problems: A Plea for a More Careful Approach to Human Assisted Reproductive Technology (ART)

DNA Methylation Patterns in the Early Human Embryo and the Epigenetic/Imprinting Problems: A Plea for a More Careful Approach to Human Assisted Reproductive Technology (ART)

An increasing number of publications indicate that babies born after IVF (in vitro fertilization) procedures have higher rates of anomalies related to imprinting/epigenetic changes, which may be attributed to suboptimal culture conditions. Appropriate maintenance of DNA methylation during the first...

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Bibliographic Details
Main Authors: Yves Menezo, Patrice Clément, Brian Dale
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
IVF
methylation
imprinting
epigenesis
maternal to zygotic transition
culture conditions
Online Access:http://www.mdpi.com/1422-0067/20/6/1342

Internet

http://www.mdpi.com/1422-0067/20/6/1342

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