Dissociated regulation of macrophage LDL receptor and apolipoprotein E gene expression by sterol
The control of apoE gene expression by sterols and the relationship between regulation of the apoE and low density lipoprotein (LDL) receptor genes were investigated in a human macrophage line. Incubation of THP1 cells in either LDL or acetylated LDL increased apoE mRNA levels 4- to 15-fold. In addi...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
1991-03-01
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| Series: | Journal of Lipid Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520420747 |