Protective human leucocyte antigen haplotype, HLA-DRB1*01-B*14, against chronic Chagas disease in Bolivia.

BACKGROUND: Chagas disease, caused by the flagellate parasite Trypanosoma cruzi affects 8-10 million people in Latin America. The mechanisms that underlie the development of complications of chronic Chagas disease, characterized primarily by pathology of the heart and digestive system, are not curre...

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Main Authors: Florencia del Puerto, Juan Eiki Nishizawa, Mihoko Kikuchi, Yelin Roca, Cinthia Avilas, Alberto Gianella, Javier Lora, Freddy Udalrico Gutierrez Velarde, Sachio Miura, Norihiro Komiya, Koji Maemura, Kenji Hirayama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3308929?pdf=render