B cells expressing IL-10 mRNA modulate memory T cells after DNA-Hsp65 immunization

B cells expressing IL-10 mRNA modulate memory T cells after DNA-Hsp65 immunization

In DNA vaccines, the gene of interest is cloned into a bacterial plasmid that is engineered to induce protein production for long periods in eukaryotic cells. Previous research has shown that the intramuscular immunization of BALB/c mice with a naked plasmid DNA fragment encoding the Mycobacterium l...

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Bibliographic Details
Main Authors: I. C. Fontoura, A.P.F. Trombone, L. P. Almeida, J. C. C. Lorenzi, R. A. M. Rossetti, T. Malardo, E. Padilha, W. Schluchting, R. L. L. Silva, A. F. Gembre, J. E. C. Fiuza, C. L. Silva, A. Panunto-Castelo, A. A. M. Coelho-Castelo
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2015-12-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
DNA-Hsp65 vaccine
Memory T cells
B cells
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015001201095&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015001201095&lng=en&tlng=en

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