Intracellular trafficking of recycling apolipoprotein E in Chinese hamster ovary cells

We have investigated apolipoprotein E (apoE) recycling in Chinese hamster ovary (CHO) cells, a peripheral cell that does not produce lipoproteins or express apoE. Using a pulse-chase protocol in which cells were pulsed with 125I-apoE-VLDL and chased for different periods, ∼30% of the apoE internaliz...

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Bibliographic Details
Main Authors: Nicole A. Braun, Peter J. Mohler, Karl H. Weisgraber, Alyssa H. Hasty, MacRae F. Linton, Patricia G. Yancey, Yan Ru Su, Sergio Fazio, Larry L. Swift
Format: Article
Language:English
Published: Elsevier 2006-06-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520332168