Complement receptor 1 (CR1, CD35) association with susceptibility to leprosy.

Complement receptor 1 (CR1, CD35) association with susceptibility to leprosy.

BACKGROUND:Pathophysiological mechanisms are still incompletely understood for leprosy, an urgent public health issue in Brazil. Complement receptor 1 (CR1) binds complement fragments C3b/C4b deposited on mycobacteria, mediating its entrance in macrophages. We investigated CR1 polymorphisms, gene ex...

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Bibliographic Details
Main Authors: Gabriela Canalli Kretzschmar, Luana Caroline Oliveira, Renato Mitsunori Nisihara, Thirumalaisamy P Velavan, Sérvio Túlio Stinghen, Ewalda R S Stahlke, Maria Luiza Petzl-Erler, Iara José T de Messias-Reason, Angelica Beate Winter Boldt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6103516?pdf=render

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http://europepmc.org/articles/PMC6103516?pdf=render

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