Molecular regulation of human IgE synthesis
Human IgE synthesis is largely dependent on the production of interleukin (IL)-4 or IL-13 and the expression of CD40 ligand. Such B cell help is not only provided by CD4+ T cells, but also by CD8+ T cells, γδ T cells, mast cells, basophils and eosinophils. The IL-4 receptor a chain (IL-4Ra) expresse...
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| Format: | Article |
| Language: | English |
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Elsevier
1999-01-01
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| Series: | Allergology International |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1323893015314751 |