Salmonella type III effector AvrA stabilizes cell tight junctions to inhibit inflammation in intestinal epithelial cells.

Salmonella Typhimurium is a major cause of human gastroenteritis. The Salmonella type III secretory system secretes virulence proteins, called effectors. Effectors are responsible for the alteration of tight junction (TJ) structure and function in intestinal epithelial cells. AvrA is a newly describ...

Full description

Bibliographic Details
Main Authors: Anne P Liao, Elaine O Petrof, Sumalatha Kuppireddi, Yun Zhao, Yinglin Xia, Erika C Claud, Jun Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2408728?pdf=render