Identification of the neutralizing epitopes of Merkel cell polyomavirus major capsid protein within the BC and EF surface loops.

Identification of the neutralizing epitopes of Merkel cell polyomavirus major capsid protein within the BC and EF surface loops.

Merkel cell polyomavirus (MCPyV) is the first polyomavirus clearly associated with a human cancer, i.e. the Merkel cell carcinoma (MCC). Polyomaviruses are small naked DNA viruses that induce a robust polyclonal antibody response against the major capsid protein (VP1). However, the polyomavirus VP1...

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Bibliographic Details
Main Authors: Maxime J J Fleury, Jérôme T J Nicol, Mahtab Samimi, Françoise Arnold, Raphael Cazal, Raphaelle Ballaire, Olivier Mercey, Hélène Gonneville, Nicolas Combelas, Jean-Francois Vautherot, Thierry Moreau, Gérard Lorette, Pierre Coursaget, Antoine Touzé
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4374900?pdf=render

Internet

http://europepmc.org/articles/PMC4374900?pdf=render

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