Intermittent Hypoxia Training Prevents Deficient Learning-Memory Behavior in Mice Modeling Alzheimer's Disease: A Pilot Study

Intermittent Hypoxia Training Prevents Deficient Learning-Memory Behavior in Mice Modeling Alzheimer's Disease: A Pilot Study

In mouse models of Alzheimer's disease (AD), normobaric intermittent hypoxia training (IHT) can preserve neurobehavioral function when applied before deficits develop, but IHT's effectiveness after onset of amyloid-β (Aβ) accumulation is unclear. This study tested the hypothesis that IHT i...

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Bibliographic Details
Main Authors: Myoung-Gwi Ryou, Xiaoan Chen, Ming Cai, Hong Wang, Marianna E. Jung, Daniel B. Metzger, Robert T. Mallet, Xiangrong Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer's disease
beta-amyloid
BDNF
cerebral cortex
erythropoietin
intermittent hypoxia
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.674688/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2021.674688/full

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