Depletion and activation of mucosal CD4 T cells in HIV infected women with HPV-associated lesions of the cervix uteri.

<h4>Background</h4>The burden of HPV-associated premalignant and malignant cervical lesions remains high in HIV+ women even under ART treatment. In order to identify possible underlying pathophysiologic mechanisms, we studied activation and HIV co-receptor expression in cervical T-cell p...

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Bibliographic Details
Main Authors: Wilbert Mbuya, Ruby Mcharo, Jacklina Mhizde, Jonathan Mnkai, Anifrid Mahenge, Maria Mwakatima, Wolfram Mwalongo, Nhamo Chiwerengo, Michael Hölscher, Tessa Lennemann, Elmar Saathoff, France Rwegoshora, Liset Torres, Arne Kroidl, Christof Geldmacher, Kathrin Held, Mkunde Chachage
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0240154