Impact of a selective cyclooxygenase-2 inhibitor, celecoxib, on cortical excitability and electrophysiological properties of the brain in healthy volunteers: A randomized, double-blind, placebo-controlled study.

Impact of a selective cyclooxygenase-2 inhibitor, celecoxib, on cortical excitability and electrophysiological properties of the brain in healthy volunteers: A randomized, double-blind, placebo-controlled study.

The inflammatory response is considered a defence mechanism against physical or infectious insults and is prevalent within the central nervous system. Seizures also result in a robust inflammatory cascade, leading to enhanced activation of excitatory synaptic networks. Ample evidence based on animal...

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Main Authors: Jung-Ah Lim, Ki-Young Jung, Boram Park, Tae-Joon Kim, Jin-Sun Jun, Keun Tae Kim, Tae-Won Yang, Soon-Tae Lee, Keun-Hwa Jung, Kon Chu, Sang Kun Lee, Kyung-Il Park
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0212689

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https://doi.org/10.1371/journal.pone.0212689

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