The Glycogen Synthase Kinase 3α and β Isoforms Differentially Regulates Interleukin-12p40 Expression in Endothelial Cells Stimulated with Peptidoglycan from Staphylococcus aureus.

Glycogen synthase kinase 3 (GSK3) is a constitutively active regulatory enzyme that is important in cancer, diabetes, and cardiovascular, neurodegenerative, and psychiatric diseases. While GSK3α is usually important in neurodegenerative and psychiatric diseases GSK3β is fundamental in the inflammato...

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Main Authors: Ricarda Cortés-Vieyra, Octavio Silva-García, Javier Oviedo-Boyso, Alejandro Huante-Mendoza, Alejandro Bravo-Patiño, Juan J Valdez-Alarcón, B Brett Finlay, Víctor M Baizabal-Aguirre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4511647?pdf=render