Synthesis of formazans from Mannich base of 5-(4-chlorophenyl amino)-2-mercapto-1,3,4-thiadiazole as antimicrobial agents

Synthesis of formazans from Mannich base of 5-(4-chlorophenyl amino)-2-mercapto-1,3,4-thiadiazole as antimicrobial agents

5-(4-Chlorophenyl amino)-2-mercapto-1,3,4-thiadiazole (I) was refluxed with formaldehyde and ammonium chloride in ethanol yielding the Mannich base 5-(4-chloro phenyl amino)-3-aminomethyl-2-mercapto-1,3,4-thiadiazole (II). Esterification with 4-chloro-(2,6-dinitro phenoxy)-ethyl acetate (III) under...

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Bibliographic Details
Main Authors: Pramilla Sah, Pratibha Bidawat, Manu Seth, Chandra Prakash Gharu
Format: Article
Language:English
Published: Elsevier 2014-04-01
Series:Arabian Journal of Chemistry
Subjects:
Mannich base
1,3,4-Thiadiazole
Formazans
Antimicrobial
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535210002285

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http://www.sciencedirect.com/science/article/pii/S1878535210002285

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