The G9a Histone Methyltransferase Inhibitor BIX-01294 Modulates Gene Expression during <i>Plasmodium falciparum</i> Gametocyte Development and Transmission

The G9a Histone Methyltransferase Inhibitor BIX-01294 Modulates Gene Expression during <i>Plasmodium falciparum</i> Gametocyte Development and Transmission

Transmission of the malaria parasite <i>Plasmodium falciparum</i> from the human to the mosquito is initiated by specialized sexual cells, the gametocytes. In the human, gametocytes are formed in response to stress signals and following uptake by a blood-feeding <i>Anopheles</i&...

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Bibliographic Details
Main Authors: Che Julius Ngwa, Meike Jutta Kiesow, Lindsey Marie Orchard, Afia Farrukh, Manuel Llinás, Gabriele Pradel
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
histone methylation
gene expression
malaria
gametocytes
transmission
Online Access:https://www.mdpi.com/1422-0067/20/20/5087

Internet

https://www.mdpi.com/1422-0067/20/20/5087

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