MicroRNA and mRNA profiling of cerebral cortex in a transgenic mouse model of Alzheimer’s disease by RNA sequencing

MicroRNA and mRNA profiling of cerebral cortex in a transgenic mouse model of Alzheimer’s disease by RNA sequencing

In a previous study, we found that long non-coding genes in Alzheimer’s disease (AD) are a result of endogenous gene disorders caused by the recruitment of microRNA (miRNA) and mRNA, and that miR-200a-3p and other representative miRNAs can mediate cognitive impairment and thus serve as new biomarker...

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Bibliographic Details
Main Authors: Li Zeng, Hai-Lun Jiang, Ghulam Md Ashraf, Zhuo-Rong Li, Rui Liu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
3′-untranslated region; alzheimer’s disease; biomarker; cerebral cortex; gene ontology; high-throughput sequencing; intracellular neurofibrillary tangles; microtubule-associated protein-τ; mirna-mrna network; presenilin 1
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=10;spage=2099;epage=2108;aulast=Zeng

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=10;spage=2099;epage=2108;aulast=Zeng

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